D-amino acid oxidase induction in the kidneys of germ-free mice.
نویسندگان
چکیده
High levels of d-amino acid oxidase activity were found in the kidneys of conventionally reared mice, whereas the enzyme was absent from the kidneys of most germ-free mice. Injection of d-alanine or monocontamination with Bacillus cereus stimulated d-amino acid oxidase activity in the kidneys of germ-free mice.
منابع مشابه
Biological role of D-amino acid oxidase and D-aspartate oxidase. Effects of D-amino acids.
D-Amino acids administered to animals are absorbed by the intestine and transported through the blood-stream to solid tissues where they are oxidized in vivo by D-amino acid oxidase and D-aspartate oxidase to produce the same compounds they do in vitro; i.e. NH3, H2O2, and the keto acid corresponding to the amino acid ingested. In the liver and kidneys of the animals, an inverse relationship ex...
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ورودعنوان ژورنال:
- Journal of bacteriology
دوره 96 3 شماره
صفحات -
تاریخ انتشار 1968